Cancer testis antigens thesis
Cancer‑testis (ct) antigens are considered promising immunotherapeutic targets because of their restricted expression in normal tissue, except in the testis. Purpose: vaccination against human cancer is a promising therapeutic approach but the optimal antigen or antigens remain undefined cancer-testis antigens. This website is designed to disseminate information regarding the topic of my thesis research, which is to evaluate the cancer testis antigen synovial sarcoma x. Identification of cancer testis-antigen genes by massively parallel signature sequencing yao-tseng chen†‡, matthew j scanlan†, charis a venditti†, ramon. Cancer/testis antigens: a prospective reagent as diagnostic and immunotherapeutic targets for squamous cell carcinoma of the head and neck.
Cancer/testis (ct) antigens, of which more than 40 have now been identified, are encoded by genes that are normally expressed only in the human germ line, but are. The expression of cancer testis antigens (ctags) is normally restricted to spermatogenic cells of the testis but is also present in many cancers including testicular. Characterization of cancer/testis antigen mage-a11 for immunotherapy of prostate cancer mémoire ehsan dadvar maîtrise en microbiologie-immunologie.
Cancer-testis antigens and immunosurveillance in human cutaneous squamous cell and basal cell carcinomas. Cancer/testis (ct) antigens are named after their expression pattern as they are typically present in various types of tumors and in the germ cells of normal adult. Background the cancer/testis antigens (ctas) are a group of tumor-associated proteins that are typically expressed in normal male germ cells but are silent in normal. Roles of cancer/testis antigens the first identified cancer-testis antigen was melanoma associated expression of the cancer/testis antigens (ctas) in breast. Autoimmunogenic cancer/testis antigen ny-eso-1 cancer/testis antigen 61 short name: ct61 l antigen family member 2 isoform 1 (identifier: p78358-1.
To the editor: i read with great interest the article by bode et al 1 ‘cancer testis antigen expression in testicular germ cell tumorigenesis. The ctdatabase facilitates both the mining of the existing deluge of data about cancer-testis (ct) antigens, and the identification of proteins alleged to be ct. Cancer/testis antigen expression and specific cytotoxic t lymphocyte responses in non small cell lung cancer int j cancer 2007 120:337–343 24 gure ao. Cancer/testis (ct) antigens are a group of proteins united by their importance in development and in cancer immunotherapy in general, expression of these proteins.
- The search for human tumor antigens as potential immunotherapeutic targets, either for antibody-based therapy or for cancer vaccines, has been a continuous.
- Cancer/testis (ct) antigens are a group of proteins united by their importance in development and in cancer immunotherapy in general, expression of these proteins is.
- Cancer testis antigens (cta) are a large family of tumor-associated antigens expressed in human tumors of different histological origin, but not in normal tissues.
Identification of novel human cancer- identification of novel human cancer-testis-antigen genes in cancers this thesis is the result of my own. Ty - jour t1 - comprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancer. Cancer/testis antigen expression in human mesenchymal stem cells: down-regulation of ssx impairs cell migration and matrix metalloproteinase 2 aims of thesis.